Correction: Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis

  • C Thomas G Appleton1, 2,

    Affiliated with

    • David D McErlain3, 4,

      Affiliated with

      • Vasek Pitelka1, 2,

        Affiliated with

        • Neil Schwartz5,

          Affiliated with

          • Suzanne M Bernier1, 6,

            Affiliated with

            • James L Henry5,

              Affiliated with

              • David W Holdsworth3, 4, 7 and

                Affiliated with

                • Frank Beier1, 2Email author

                  Affiliated with

                  Arthritis Research & Therapy200810:407

                  DOI: 10.1186/ar2513

                  Published: 22 September 2008

                   

                  After publication of our recent article [1], it has been brought to our attention that four panels in Figure 1 have been mislabeled. Images (c) and (e) are femurs, rather than tibias. Similarly, images (d) and (f) should be labelled as tibias.

                  As such the figure legend should read as follows:

                  Forced mobilization apparatus and macroscopic analysis of joint degradation. (a) Following sham (control) or OA surgery, FM animals underwent forced mobilization. Animals walked on a rotating cylinder for 30 min, three times per week. (b) FM forces the maximal extension and flexion of the knee joint (white arrow). To assess macroscopic changes to the articular surface, knee joints were dissected 4 weeks after surgery and photographed. Representative images from sham (c) femurs and (d) tibias, and ipsilateral (e) femurs and (f) tibias are shown. Surface abrasions (black arrow) and fibrotic tissue (arrow head) were observed in ipsilateral surfaces, compared with the smooth, glassy appearance in shams. Scale bar applies to panels c-f. FM, forced mobilization; OA, osteoarthritis.

                  Authors’ Affiliations

                  (1)
                  CIHR Group in Skeletal Development & Remodeling, Schulich School of Medicine & Dentistry, The University of Western Ontario
                  (2)
                  Department of Physiology & Pharmacology, Schulich School of Medicine & Dentistry, The University of Western Ontario
                  (3)
                  Imaging Research Laboratories, Robarts Research Institute
                  (4)
                  Department of Medical Biophysics, Schulich School of Medicine & Dentistry, The University of Western Ontario
                  (5)
                  Micheal G DeGroote Institute for Pain Research & Care, McMaster University
                  (6)
                  Department of Anatomy & Cell Biology, Schulich School of Medicine & Dentistry, The University of Western Ontario
                  (7)
                  Department of Diagnostic Radiology & Nuclear Medicine, Schulich School of Medicine & Dentistry, The University of Western Ontario

                  References

                  1. Appleton CTG, McErlain DD, Pitelka V, Schwartz N, Bernier SM, Henry JL, Holdsworth DW, Frank Beier F: Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis. Arthritis Res Ther 2007, 9:R13.View ArticlePubMed

                  Copyright

                  © BioMed Central Ltd 2008

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