Correction: Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus

  • Kamini Shah1,

    Affiliated with

    • Won-Woo Lee1, 2,

      Affiliated with

      • Seung-Hyun Lee1, 3,

        Affiliated with

        • Sang Hyun Kim1, 4,

          Affiliated with

          • Seong Wook Kang1, 5,

            Affiliated with

            • Joe Craft1, 6 and

              Affiliated with

              • Insoo Kang1

                Affiliated with

                Arthritis Research & Therapy201012:402

                DOI: 10.1186/ar2996

                Published: 12 May 2010

                Following publication of our recent article [1], we noticed an error in Figure 4. In part (e), the SLEDAI score for the frequency of CD4+ T cells expressing CCR4 and/or CCR6 in a patient with SLE at the times of low disease activities should be "6", rather than "4". The corrected Figure 4 is given here overleaf as Figure 1.
                http://static-content.springer.com/image/art%3A10.1186%2Far2996/MediaObjects/13075_2010_Article_2831_Fig1_HTML.jpg
                Figure 1

                Patients with SLE have an increased frequency of CD4 + CCR4 + CCR6 + T cells. The frequency of CCR4+ CCR6+CD4+ T cells in peripheral blood was analyzed in patients with SLE and healthy control subjects by using flow cytometry. (a) Representative dot plots showing CD4+ T cells expressing CCR4 and CCR6. (b) The frequency (%) of CD4+CCR4+CCR6+ T cells in patients with SLE (n = 14) and healthy control subjects (HC, n = 25). (c) Correlation between the frequencies of CD4+IL-17+ T cells and CD4+CCR4+CCR6+ T cells in patients with SLE (n = 11). (d) Correlation between the frequency of CD4+CCR4+CCR6+ T cells and SLEDAI score in patients with SLE (n = 14). (e) Representative dot plots showing the frequency of CD4+ T cells expressing CCR4 and/or CCR6 in patients with SLE at the times of high and low disease activities (SLEDAI score, 16 and 6, respectively). Representative data from three patients with SLE. Numbers in dot plots indicate the frequency of cells for each quadrant. Bars show the means.

                Authors’ Affiliations

                (1)
                Department of Internal Medicine, Yale University School of Medicine
                (2)
                Department of Microbiology, College of Medicine, Seoul National University
                (3)
                Department of Microbiology, Konkuk University School of Medicine
                (4)
                Department of Microbiology, College of Medicine, Kangwon National University
                (5)
                Department of Internal Medicine, College of Medicine, Chungnam National University
                (6)
                Department of Immunobiology, Yale University School of Medicine

                References

                1. Shah K, Lee WW, Lee SH, Kim SH, Kang SW, Craft J, Kang I: Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus. Arthritis Research & Therapy 2010, 12:R53.View Article

                Copyright

                © BioMed Central Ltd 2010

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