Volume 8 Supplement 1

Gout and Hyperuricemia


Edited by Robert Terkeltaub and Bruce Cronstein

Supported by an educational grant from TAP Pharmaceuticals Inc.

  1. Review

    A concise history of gout and hyperuricemia and their treatment

    First identified by the Egyptians in 2640 BC, podagra (acute gout occurring in the first metatarsophalangeal joint) was later recognized by Hippocrates in the fifth century BC, who referred to it as 'the unwal...

    George Nuki and Peter A Simkin

    Arthritis Research & Therapy 2006 8(Suppl 1):S1

    Published on: 12 April 2006

  2. Review

    Epidemiology, risk factors, and lifestyle modifications for gout

    Gout affects more than 1% of adults in the USA, and it is the most common form of inflammatory arthritis among men. Accumulating data support an increase in the prevalence of gout that is potentially attributa...

    Kenneth G Saag and Hyon Choi

    Arthritis Research & Therapy 2006 8(Suppl 1):S2

    Published on: 12 April 2006

  3. Review

    The inflammatory process of gout and its treatment

    Gouty arthritis is a characteristically intense acute inflammatory reaction that erupts in response to articular deposits of monosodium urate (MSU) crystals. Important recent molecular biologic advances in thi...

    Bruce N Cronstein and Robert Terkeltaub

    Arthritis Research & Therapy 2006 8(Suppl 1):S3

    Published on: 12 April 2006

  4. Review

    Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics

    Although dietary, genetic, or disease-related excesses in urate production may contribute to hyperuricemia, impaired renal excretion of uric acid is the dominant cause of hyperuricemia in the majority of patie...

    Robert Terkeltaub, David A Bushinsky and Michael A Becker

    Arthritis Research & Therapy 2006 8(Suppl 1):S4

    Published on: 12 April 2006