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Table 4 Association between the change in DAS28 score and the presence of multimorbidity according to the Charlson Comorbidity Index score

From: Impact of multimorbidity on the first ts/bDMARD effectiveness and retention rate after two years of follow-up in patients with rheumatoid arthritis from the BIOBADASER registry

 

Crude linear regression

Adjusted linear regression

Beta coefficient (95%CI)

p-value

Beta coefficient (95%CI)

p-value

Multimorbidity (CCI score ≥ 3)

0.37 (0.17 to 0.57)

0.002

0.33 (0.07 to 0.58)

0.011

Sex (female)

-

-

0.35 (0.18 to 0.52)

 < 0.001

Age at the drug initiation

-

-

0.01 (0.01 to 0.02)

 < 0.001

1-year timepoint

-

-

-1.45 (-1.82 to -1.09)

 < 0.001

2-year timepoint

-

-

-1.79 (-2.22 to -1.35)

0.001

  1. CCI Charlson Comorbidity Index, 95%CI 95% Confidence Interval, DAS28 disease activity score 28