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Table 1 Synovial biopsy and the determination of diagnosis or outcome in established rheumatoid arthritis

From: Are synovial biopsies of diagnostic value?

Synovial tissue Clinical association References
Number of macrophages Radiographic outcome [27, 43]
TNF-α Response to TNF-α blockade [41]
IL-10 Radiographic outcome [46]
VEGF Radiographic outcome [48]
  1. IL, interleukin; TNF, tumour necrosis factor; VEGF, vascular endothelial growth factor.