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Table 1 Major physiologic functions of B lymphocytes

From: Roles of B cells in rheumatoid arthritis

Precursors of antibody producing plasma cells
Provide noncognate help for T cell activation
Efficient antigen-presenting cells, especially for recall antigens
Produce cytokines (i.e. IL-4 and IL-10) that support the survival other mononuclear cells
Generate and respond to chemotactic factors responsible for leukocyte migration and development of granulation tissue
Sustain immunologic memory