Figure 1From: Ageing, autoimmunity and arthritis: Perturbations of TCR signal transduction pathways with ageing – a biochemical paradigm for the ageing immune systemSchematic conceptualization of the changes with ageing in lipid raft composition following plasma membrane changes in cholesterol content and their effects on early signalling events. LAT, linker of activated T cells; PKC, protein kinase C; TCR, T-cell receptor.Back to article page