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Table 3 Guidelines for conditioning regimens before HSC transplantation

From: Immune ablation and stem-cell therapy in autoimmune disease - Clinical experience

Cyclophosphamide 50 mg/kg for 4 days at a 1-h infusion from days -5
   to -2 before the transplantation; this is standard treatment for
   aplastic anaemia. Antithymocyte globulin may or may not be added
Cyclosphamide 60 mg/kg for 2 days at 1-h infusion followed by total
   body irradiation, as currently used at the treating centre
Busulfan 16 mg/kg orally over 4 days in 16 doses of 1 mg/kg each,
   followed by cyclophosphamide 60 mg/kg a 1-h infusion for 2 days;
   anticonvulsant prophylaxis is required
Combination chemotherapy: BEAM (BCNU 300 mg/m2 intravenously
   day -7; VP-16 250 mg/m2 per day, divided over two doses each
   day, from days -7 to -4; Ara-C 200 mg/m2 per day, divided over
   two doses each day, on days -7, -6 and -4; melphalan 140
   mg/m2 intravenously on day -3)