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Figure 5 | Arthritis Res Ther

Figure 5

From: Enhanced expression of interferon-inducible protein 10 associated with Th1 profiles of chemokine receptor in autoimmune pulmonary inflammation of MRL/lprmice

Figure 5

Time course of CXCR3 transcription. Whole RNA was isolated from lung tissues of 1- and 4-month-old MRL/lpr, MRL/+, and B6 mice; transcribed mRNA was amplified by RT-PCR. (a) Representative expression of CXCR3 mRNA and Southern blot hybridization with internal probes; GAPDH primers were used as an internal control. Data are representative of three independent experiments. Lane M: molecular weight markers (100-base-pair ladder). (b) CXCR3 transcripts were quantitated and normalized to GAPDH as the CXCR3/GAPDH transcripts ratio. Data are expressed as mean ± SEM of three independent experiments; *P < 0.05 vs B6 mice (4 months); the difference between MRL/lpr and MRL/+ mice (4 months) was not statistically significant. GAPDH, glyceraldehyde-3-phosphate dehydrogenase; PCR, polymerase chain reaction.

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