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Table 2 Spearman's rank correlations between anti-CRP levels (optical density) and SLEDAI, modified SLEDAI, serum levels of anti-DNA antibodies, complement components, CRP, and blood cell counts respectively

From: Serum levels of autoantibodies against monomeric C-reactive protein are correlated with disease activity in systemic lupus erythematosus

Analysis BÅ UO IS* HG AM CM MS AR* BB* DD Total Anti-CRP+
CRP n.s. n.s. n.s. n.s. n.s. n.s. < 0.05 n.s. n.s. n.s. n.s. 1/7
mSLEDAI < 0.01 n.s. n.s. n.s. < 0.05 < 0.01 < 0.02 n.s. n.s. n.s. < 0.001 4/7
SLEDAI < 0.002 n.s. n.s. n.s. n.s. < 0.01 < 0.02 n.s. n.s. n.s. < 0.001 3/7
C1q n.s. n.s. n.s. < 0.05 n.s. < 0.05 n.s. n.s. < 0.05 n.s. < 0.002 2/7
C3 n.s. n.s. n.s. n.s. n.s. < 0.02 n.s. n.s. n.s. n.s. < 0.005 1/7
C4 n.s. n.s. n.s. n.s. n.s. n.s. n.s. n.s. n.s. n.s. < 0.002 0/7
Platelet count n.s. < 0.05 n.s. < 0.05 n.s. n.s. n.s. n.s. n.s. n.s. n.s. 2/7
White blood cell count n.s. n.s. n.s. n.s. n.s. < 0.05 < 0.02 n.s. n.s n.s. n.s. 2/7
Lymphocyte count n.s. n.s. n.s. n.s. n.s. < 0.02 < 0.05 < 0.05 n.s. n.s. < 0.005 2/7
Anti-dsDNA (Farr) < 0.002 n.s. n.s. n.s. n.s. < 0.05 < 0.05 n.s. < 0.01 n.s. < 0.001 3/7
Anti-dsDNA (commercial ELISA) < 0.002 n.s. n.s. n.s. n.s. < 0.002 < 0.05 n.s. n.s. < 0.05 < 0.01 4/7
Anti-dsDNA ('in-house' ELISA) < 0.001 n.s. n.s. < 0.02 n.s. < 0.01 < 0.05 n.s. n.s. n.s. < 0.001 4/7
Correlation in at least 1 variable Yes Yes No Yes Yes Yes Yes Yes Yes Yes   7/7
  1. Results (P values) are presented at the individual level and for the whole patient material (n = 10). Positive correlations are given as bold P values and inverse correlations are shown in italics. The three consistently anti-CRP-negative cases are asterisked. In the last column, '4/7 anti-CRP+', for example, means that four of seven anti-CRP-positive patients had anti-CRP levels correlating to this particular variable. anti-CRP, anti-C-reactive protein autoantibody; CRP, C-reactive protein; mSLEDAI, modified systemic lupus erythematosus disease activity index; n.s., not significant; SLEDAI, systemic lupus erythematosus disease activity index.
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