Figure 2
![Figure 2](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Far1038/MediaObjects/13075_2003_Article_1028_Fig2_HTML.jpg)
IL-17 induces production of (b) IL-6 and (c) IL-8, but not of (a) IL-15, by synovial fibroblasts from five RA patients. In vitro stimulation with 10 ng/ml IL-17 for 12 hours induced two- to six-fold increases in the levels of IL-6 and IL-8 in the culture supernatant of synovial fibroblasts isolated from RA patients, while the level of IL-15 remained unchanged. Open bar, unstimulated FLS; filled bar, IL-17-stimulated FLS. FLS, fibroblast-like synoviocytes; RA, rheumatoid arthritis.