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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Gene therapy for established murine collagen-induced arthritis by local and systemic adenovirus-mediated delivery of interleukin-4

Figure 3

Periarticular injection of Ad-mIL-4 into the hind leg ankle jointsconferred a therapeutic effect in the untreated, front paws. The arthritic miceinjected in the hind leg ankle joints with Ad-mIL-4, Ad-eGFP or saline wereevaluated for the severity of arthritis in either the hind, treated paws(a) or front, untreated paws (b). The macroscopic score (meanĀ± standard deviation) is expressed as a cumulative value for the two paws,with a maximum possible score of 8.

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