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Table 2 Clinical central nervous system (CNS) manifestations in systemic lupus erythematosus patients included in the study

From: Decreased levels of soluble amyloid β-protein precursor and β-amyloid protein in cerebrospinal fluid of patients with systemic lupus erythematosus

CNS manifestations

NPSLE (n = 36)

No NPSLE (n = 71)

Antiphospholipid antibody syndrome (n = 7)

Acute confusional state

2 (6%)

1 (1.5%)

0 (0%)

Anxiety disorder

1 (3%)

5 (7%)

0 (0%)

Aseptic meningitis

1 (3%)

0 (0%)

0 (0%)

Cerebrovascular disease

5 (14%)

7 (10%)

4 (57%)

Cognitive dysfunction

7 (19%)

19 (27%)

0 (0%)

Demyelinating syndrome

3 (8%)

1 (1.5%)

0 (0%)

Headache

8 (22%)

28 (39%)

3 (43%)

Mood disorders

7 (19%)

10 (14%)

1 (14%)

Movement disorder

2 (6%)

0 (0%)

0 (0%)

Myastenia gravis

0 (0%)

2 (3%)

0 (0%)

Myelopathy

2 (6%)

0 (0%)

0 (0%)

Polyneuropathy

0 (%)

2 (3%)

0 (0%)

Mononeuropathy

0 (0%)

1 (1.5%)

0 (0%)

Neuropathy

0 (0%)

2 (3%)

1 (14%)

Psychosis

2 (6%)

1 (1.5%)

0 (0%)

Seizure disorders

6 (17%)

0 (0%)

0 (0%)

  1. Each patient may have had multiple clinical manifestations of the CNS involvement. NPSLE, neuropsychiatric systemic lupus erythematosus.