Table 1 Diagnostic performance of serum markers using different cut offs
Antibody | Cutoff | Sensitivity (%) | Specificity (%) | PPV (%) |
|---|---|---|---|---|
PepA | Low | 63.6 | 90.6 | 60.7 |
PepB | Â | 64.3 | 90.0 | 59.0 |
RF | Â | 69.2 | 90.1 | 61.5 |
PepA | Intermediate | 62.9 | 95.1 | 74.4 |
PepB | Â | 61.5 | 95.1 | 73.3 |
RF | Â | 55.2 | 94.6 | 69.9 |
PepA | High | 58.7 | 98.1 | 87.5 |
PepB | Â | 48.3 | 98.1 | 85.2 |
RF | Â | 42.0 | 97.8 | 81.1 |
PepA | Very high | 41.3 | 99.0 | 90.8 |
PepB | Â | 37.1 | 99.0 | 89.8 |
RF | Â | 21.0 | 99.0 | 83.3 |