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Table 1 Weight change after 9 weeks of treatment in female Sprague–Dawley rats (cohorts A and B) assessed in the studies of the effects of ovariectomy on cartilage

From: Ovariectomized rats as a model of postmenopausal osteoarthritis: validation and application

    

Weight (g)

Cohort

Treatment

Age at start (months)

n

Of body at start

Of body at end

Of uterus at end

A

OVX

5

10

292 ± 20

370 ± 28**

0.05 ± 0.02***

 

Shama

5

8

295 ± 28

324 ± 34

0.23 ± 0.03

B

OVX

7

9

327 ± 28

384 ± 24**

0.25 ± 0.20**

 

Shama

7

8

324 ± 29

342 ± 40

0.80 ± 0.45

  1. Values are means ± SD. Difference between OVX and sham-operated rats were assessed using the nonparametric Mann-Whitney U test: aSham-operated. **P < 0.01, ***P < 0.001. OVX, ovariectomized.