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Figure 1 | Arthritis Res Ther

Figure 1

From: Treatment with recombinant interferon-β reduces inflammation and slows cartilage destruction in the collagen-induced arthritis model of rheumatoid arthritis

Figure 1

Effect of systemically delivered IFN-β at the onset of arthritis in mice with collagen-induced arthritis. (a) Clinical score (mean ± SEM) was assessed on a scale of 0 to 3.5 (as described in Materials and methods), and (b) hind paw swelling (mean ± SEM) of the first arthritic paw was monitored during the course of disease using calipers. On day 7 after the start of the treatment, differences between all treatment groups and the control group were statistically significant (P = 0.005) (Kruskal–Wallis test). Arrows mark the first day of treatment. *Statistically significant difference. SEM, standard error of the mean.

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Arthritis Research & Therapy

ISSN: 1478-6362

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