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Table 2 Proportion of IL-10 producing CD4+CD25+ T cells in lymph nodes and spleen

From: Induction of IL-10-producing CD4+CD25+T cells in animal model of collagen-induced arthritis by oral administration of type II collagen

  % CD4+CD25+ IL-10-positive cells
Site Without CII stimulation With CII stimulation
Peyer's patch   
   Normal 0.17 ± 0.12 0.14 ± 0.06
   CIA 1.6 ± 0.7 3.6 ± 0.2
   Tolerized 2.4 ± 1.6 6.8 ± 1.2
Mesentric lymph node   
   Normal 0.35 ± 0.35 0.5 ± 0.28
   CIA 0.85 ± 0.35 1.8 ± 0.5
   Tolerized 2.95 ± 1.06 7.9 ± 1.48
Spleen   
   Normal 0.13 ± 0.04 0.25 ± 1.3
   CIA 0.15 ± 0.07 3.85 ± 0.63
   Tolerized 2.95 ± 1.62 15.5 ± 4.5
  1. Values are expressed as mean ± standard deviation, calculated from three independent measurements. CIA, collagen-induced arthritis; CII, type II collagen.