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Table 2 Proportion of IL-10 producing CD4+CD25+ T cells in lymph nodes and spleen

From: Induction of IL-10-producing CD4+CD25+T cells in animal model of collagen-induced arthritis by oral administration of type II collagen

 

% CD4+CD25+ IL-10-positive cells

Site

Without CII stimulation

With CII stimulation

Peyer's patch

  

   Normal

0.17 ± 0.12

0.14 ± 0.06

   CIA

1.6 ± 0.7

3.6 ± 0.2

   Tolerized

2.4 ± 1.6

6.8 ± 1.2

Mesentric lymph node

  

   Normal

0.35 ± 0.35

0.5 ± 0.28

   CIA

0.85 ± 0.35

1.8 ± 0.5

   Tolerized

2.95 ± 1.06

7.9 ± 1.48

Spleen

  

   Normal

0.13 ± 0.04

0.25 ± 1.3

   CIA

0.15 ± 0.07

3.85 ± 0.63

   Tolerized

2.95 ± 1.62

15.5 ± 4.5

  1. Values are expressed as mean ± standard deviation, calculated from three independent measurements. CIA, collagen-induced arthritis; CII, type II collagen.