| |
% CD4+CD25+ IL-10-positive cells
|
|---|
|
Site
|
Without CII stimulation
|
With CII stimulation
|
|---|
|
Peyer's patch
| | |
|
Normal
|
0.17 ± 0.12
|
0.14 ± 0.06
|
|
CIA
|
1.6 ± 0.7
|
3.6 ± 0.2
|
|
Tolerized
|
2.4 ± 1.6
|
6.8 ± 1.2
|
|
Mesentric lymph node
| | |
|
Normal
|
0.35 ± 0.35
|
0.5 ± 0.28
|
|
CIA
|
0.85 ± 0.35
|
1.8 ± 0.5
|
|
Tolerized
|
2.95 ± 1.06
|
7.9 ± 1.48
|
|
Spleen
| | |
|
Normal
|
0.13 ± 0.04
|
0.25 ± 1.3
|
|
CIA
|
0.15 ± 0.07
|
3.85 ± 0.63
|
|
Tolerized
|
2.95 ± 1.62
|
15.5 ± 4.5
|
- Values are expressed as mean ± standard deviation, calculated from three independent measurements. CIA, collagen-induced arthritis; CII, type II collagen.
