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Table 1 Characteristics of systemic sclerosis patients (n = 40)

From: Nifedipine decreases sVCAM-1 concentrations and oxidative stress in systemic sclerosis but does not affect the concentrations of vascular endothelial growth factor or its soluble receptor 1

Characteristic

Value

Cutaneous form of the disease: limited / diffuse

23 (57) / 17 (43)

Digital pitting scars

6 (15)

Pulmonary arterial pressure (PAP)

 

   mmHg [mean ± SD (range)]

33 ± 6 (21–48)

   >40 mmHg

6 (15)

Pulmonary fibrosis (computed tomography scan)

16 (40)

Forced vital capacity below 75% of normal values

9 (23)

Decreased carbon monoxide diffusing capacity (DLCO/Hb <75%)

16 (40)

Left ventricular ejection fraction (%) (mean ± SD%)

62 ± 8

Antinuclear antibodies ≥1/160

38 (92)

Anti-topoisomerase I antibodies/anti-centromere antibodies

12/7

Creatininaemia (μmol) (mean ± SD)

79 ± 13

Erythrocyte sedimentation rate (mm/1st hour) (mean ± SD)

21 ± 18

C-reactive protein (mg/l) (mean ± SD)

11 ± 16

Ongoing low-dose prednisone (no. patients) (mean mg/day ± SD)

14 (7.4 ± 2)

Ongoing angiotensin-converting enzyme inhibitors (no. patients)

7

Ongoing low-dose aspirin therapy (no. patients)

25

  1. Values are number (%) of patients unless otherwise indicated. DLCO, carbon monoxide diffusion in the lung; Hb, hemoglobin.