Serum constituent | Controls (n = 20) | SSc patients at baseline (n = 40) | P (Mann–Whitney test) |
---|---|---|---|
sVCAM-1 (pg/ml) | 465.5 (378–619) | 712 (362–1034) | P < 0.0001 |
Carbonyl residues (nmol/mg protein) | 0.34 (0.15–0.64) | 0.83 (0.37–1.48) | P < 0.0001 |
AOPP (μmol/l of chloramine-T equivalents) | 75.5 (21–91) | 109.1 (50–281) | P < 0.0001 |
VEGF (pg/ml) | 221 (19–499) | 573.5 (26–1915) | P = 0.0001 |
sVEGFR-1 (pg/ml) | 19 (8–73) | 45 (10–1140) | P = 0.0025 |