Table 3 Serum concentrations of vascular markers in patients with systemic sclerosis (SSc) at baseline and after nifedipine treatment
Serum constituent | Baseline (n = 20) | After nifedipine treatment (n = 20) | P (Wilcoxon test) |
|---|---|---|---|
sVCAM-1 (pg/ml) | 728.7 (450–1034) | 635 (312–890) | P = 0.0001 |
Carbonyl residues (nmol/mg protein) | 0.69 (0.37–1.08) | 0.57 (0.33–0.86) | P = 0.0006 |
AOPP (μmol/l of chloramine-T equivalents) | 111.35 (50.5–257.6) | 89.25 (28–186.4) | P = 0.004 |
VEGF (pg/ml) | 463 (26–1251) | 421.5 (47–2032) | P = 0.97 |
sVEGFR-1 (pg/ml) | 46 (10–587) | 32 (9–452) | P = 0.43 |