Serum constituent
|
Baseline (n = 20)
|
After nifedipine treatment (n = 20)
|
P (Wilcoxon test)
|
---|
sVCAM-1 (pg/ml)
|
728.7 (450–1034)
|
635 (312–890)
|
P = 0.0001
|
Carbonyl residues (nmol/mg protein)
|
0.69 (0.37–1.08)
|
0.57 (0.33–0.86)
|
P = 0.0006
|
AOPP (μmol/l of chloramine-T equivalents)
|
111.35 (50.5–257.6)
|
89.25 (28–186.4)
|
P = 0.004
|
VEGF (pg/ml)
|
463 (26–1251)
|
421.5 (47–2032)
|
P = 0.97
|
sVEGFR-1 (pg/ml)
|
46 (10–587)
|
32 (9–452)
|
P = 0.43
|
- Values are median (range) of serum concentrations in patients. AOPP, advanced oxidation protein products; sVCAM-1, soluble vascular cell adhesion molecule 1; sVEGFR-1, soluble VEGF receptor 1; VEGF, vascular endothelial growth factor.