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Table 2 Results of logistic regression analyses of anti-CCP antibodies (anti-CCP Ab) or rheumatoid factor (RF) of IgG, IgM, or IgA isotype and shared epitope (SE) in predicting rheumatoid arthritis, analysed in individuals who later developed the disease and in controls.

From: A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis

Combinations of variables

Patients (no.)

Controls (no.)

OR

95%CI

SE- and anti-CCP Ab-

17

71

1.0

 

SE+ and anti-CCP Ab-

18

39

1.9

0.9–4.2

SE- and anti-CCP Ab+

6

1

25.1

2.8–222.2

SE+ and anti-CCP Ab+

16

1

66.8

8.3–539.4

SE- and IgA-RF-

12

67

1.0

 

SE+ and IgA-RF-

20

38

2.9

1.3–6.7

SE- and IgA-RF+

11

5

12.3

3.6–41.7

SE+ and IgA-RF+

14

2

39.2

7.9–193.9

SE- and IgM-RF-

18

71

1.0

 

SE+ and IgM-RF-

26

38

2.6

1.2–5.2

SE- and IgM-RF+

5

5

3.7

0.99–14.3

SE+ and IgM-RF+

8

2

14.9

2.9–76.3

SE- and IgG-RF-

19

67

1.0

 

SE+ and IgG-RF-

28

39

2.5

1.3–5.1

SE- and IgG-RF+

4

5

2.8

0.7–11.6

SE+ and IgG-RF+

6

1

21.2

2.4–186.5

  1. CI, confidence interval; OR odds ratio.