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Figure 1 | Arthritis Research & Therapy

Figure 1

From: The effects of 1α,25-dihydroxyvitamin D3 on matrix metalloproteinase and prostaglandin E2 production by cells of the rheumatoid lesion

Figure 1

Immunolocalization of the vitamin D receptor (VDR) in rheumatoid tissues. (a) Immunolocalization of VDR in rheumatoid synovium. Note positive red immunostaining of fibroblastic cells. (Counterstain Harris's haematoxylin; bar = 25 μm.) (b) Demonstration of VDR in cartilage from a rheumatoid joint. Note both positive and negative chondrocytes. (Counterstain Harris's haematoxylin; bar = 20 μm.) (c) VDR immunolocalization at the cartilage-pannus junction; cells within both pannus tissue and cartilage can be seen to be expressing the receptor. (Counterstain toluidine blue; bar = 25 μm.)

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