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Table 2 Comparative effects of 1α,25-dihydroxyvitamin D3 (1α,25D3) on Interleukin (IL)-1-stimulated prostaglandin E2 production by rheumatoid synovial fibroblasts and human articular chondrocyte in vivo

From: The effects of 1α,25-dihydroxyvitamin D3 on matrix metalloproteinase and prostaglandin E2 production by cells of the rheumatoid lesion

 

Fibroblasts

Chondrocytes

Control

1

1

+ 1α,25D3

  1.23 ± 0.16

1.35 ± 0.25

+ IL-1

  7.07 ± 1.09

  3.7 ± 1.05

+ IL-1 + 1α,25D3

1.61 ± 0.7

4.23 ± 1.10

  1. Data given are normalized relative to control values and are expressed ± SEM for three cultures of each cell type.
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Arthritis Research & Therapy

ISSN: 1478-6362

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