Figure 4
From: A proinflammatory role for Fas in joints of mice with collagen-induced arthritis
Changes in the development of arthritis are not due to changes in B-cell function. Titers of collagen-specific IgG antibodies were determined in sera of DBA-lpr/lpr mice (n = 15) and DBA-lpr/+ control mice (n = 11) before immunization (a) and at 20 days (b) and 47 days (c) after immunization with collagen in complete Freund's adjuvant. Horizontal lines indicate medians. Significant differences between the two groups were seen only at day 0 (*P < 0.05).