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Table 5 Comparison of estrogen receptor-α gene haplotypes in osteoarthritis patients and control individuals

From: Estrogen receptor-α gene haplotype is associated with primary knee osteoarthritis in Korean population

Haplotype Controls OA patients
  Total Women Men Total Women Men
TAG 0.41 0.44 0.37 0.41 0.42 0.40
TAA 0.09 0.12 0.05 0.17 0.18 0.14
TGG 0.09 0.09 0.08 0.05 0.05 0.05
TGA 0.03 0.03 0.02 <0.01 <0.01 <0.01
CAG 0.25 0.18 0.31 0.18 0.18 0.18
CAA 0.06 0.06 0.06 0.05 0.04 0.07
CGG 0.06 0.06 0.08 0.10 0.10 0.09
CGA 0.02 0.01 0.02 0.04 0.02 0.07
     df = 7, χ2 = 21.48; Pa = 0.003 df = 7, χ2 = 8.22; Pa = 0.314 df = 7, χ2 = 16.76; Pa = 0.019
  1. A total of 397 control individuals and 151 osteoarthritis (OA) patients were included in the study. Values given are haplotype frequencies. aP values for overall difference in haplotype distribution between OA patients and control individuals were calculated using the EH program [23]. df, degrees of freedom.