Figure 3

Nociceptive behaviour of the rats in different experimental groups. (a) Description of the gait, scored as follows: 4, no walking; 3, walking on three legs; 2, limping with the injected leg; 1, limping after pressure on the knee; 0, normal walking. (b) Withdrawal response of the injected and the contralateral knee on local stimulation of the knee with a mechanical device, scored as follows: 3, response to pressure in the range 75–150 g; 2, response to pressure in the range 150–200 g; 1, response to pressure in the range 200–250 g; 0, no response to pressure of more than 250 g. The symbols show mean scores and standard deviations. In (a) the standard deviation was zero at most time points.