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Figure 8 | Arthritis Research & Therapy

Figure 8

From: Monoarticular antigen-induced arthritis leads to pronounced bilateral upregulation of the expression of neurokinin 1 and bradykinin 2 receptors in dorsal root ganglion neurons of rats

Figure 8

Distribution of the relative grey values of DRG neurons ipsilateral and contralateral to the injected knee with BK–gold binding. (a) Neurons (n = 800, from eight cultures) from control incubations treated with an excess of BK that was administered together with BK–gold. (b) Neurons (n = 500, from five cultures) from untreated control animals. (c) Neurons (n = 300, from three cultures) from immunized animals without knee injection. (d) Neurons (n = 500, from five cultures) from AIA rats (3 days). (e) Neurons (n = 300, from three cultures) from AIA rats (42 days). White bars, neurons exhibiting grey densities that were in the range of those observed in neurons from control incubations; black bars, neurons exhibiting grey densities that were higher than those observed in the neurons from control incubations.

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