Monoarticular antigen-induced arthritis leads to pronounced bilateral upregulation of the expression of neurokinin 1 and bradykinin 2 receptors in dorsal root ganglion neurons of rats

Table 2 Expression of bradykinin 1 and bradykinin 2 receptors in DRGs L1–L5

		Percentage of labelled neurons
Experimental group	Test site	BK–gold	BK–gold + BK1 agonist	BK–gold + BK2 agonist
Untreated control animals	i.l.	38.8 ± 7.0	38.0 ± 2.4	0
	c.l.	40.4 ± 0.9	41.6 ± 4.6	1.2 ± 1.8
Immunized rats without knee injection	i.l.	42.0 ± 1.4	38.8 ± 2.3	0
	c.l.	41.6 ± 5.2	38.8 ± 6.1	0
Rats at 3 days of AIA	i.l.	77.0 ± 3.4	83.4 ± 2.9	0.4 ± 0.9
	c.l.	88.0 ± 4.7	88.0 ± 4.7	1.6 ± 2.1
Rats at 42 days of AIA	i.l.	74.8 ± 4.8	71.6 ± 8.9	0.4 ± 0.9
	c.l.	38.8 ± 2.3	38.0 ± 2.5	1.6 ± 3.6

Values shown are the means and standard deviations. Abbreviations: i.l., ipsilateral to injected knee; c.l., contralateral to injected knee.

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