Figure 4From: Critical role of the major histocompatibility complex and IL-10 in matrilin-1-induced relapsing polychondritis in miceAnticollagen type II antibody response after immunization with matrilin-1 in (B10.Q × DBA/1)F1 B10.Q mice devoid of IL-10 through gene deletion, and their heterozygous littermates. Sera were analyzed for total IgG levels at day 35 after immunization. For detailed information on the experimental setup, see Materials and methods.Back to article page