Table 1 Susceptibility of mouse strains to immunization with matrilin-1, as shown by their development of matrilin-1-induced relapsing polychondritis (MIRP)
Mouse strain | MHC | Gender | n | Incidence of disease (%) | Mean maximum disease score | Day of onset of symptoms |
|---|---|---|---|---|---|---|
QD | H2 q | m | 12 | 92 | 4.8 ± 0.4a | 41 ± 1b |
B10.Q | H2 q | m | 16 | 56 | 2.6 ± 0.7 | 46 ± 4 |
B10.Q | H2 q | f | 8 | 25 | 2.0 ± 0 | 41 ± 0 |
C3H.Q | H2 q | m | 9 | 33 | 3.7 ± 1.2 | 46 ± 3 |
DBA/1 | H2 q | m | 12 | 50 | 3.2 ± 0.5 | 55 ± 8c |
Balb/c | H2 d | m | 5 | 0 | ||
NOD | H2 g7 | m | 10 | 0 | ||
B10.P | H2 p | m | 5 | 40 | 3.0 ± 1.0 | 45 ± 0 |
B10.RIII | H2 r | m | 8 | 25 | 2.0 ± 0 | 47 ± 2 |
B10.V | H2 v | m | 5 | 0 | ||
B10 | H2 b | m | 5 | 0 | ||
B10.F | H2 f | m | 5 | 0 | ||
B10.U | H2 u | m | 1 | 0 |