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Table 1 Susceptibility of mouse strains to immunization with matrilin-1, as shown by their development of matrilin-1-induced relapsing polychondritis (MIRP)

From: Critical role of the major histocompatibility complex and IL-10 in matrilin-1-induced relapsing polychondritis in mice

Mouse strain MHC Gender n Incidence of disease (%) Mean maximum
disease score
Day of onset of
symptoms
QD H2 q m 12 92 4.8 ± 0.4a 41 ± 1b
B10.Q H2 q m 16 56 2.6 ± 0.7 46 ± 4
B10.Q H2 q f 8 25 2.0 ± 0 41 ± 0
C3H.Q H2 q m 9 33 3.7 ± 1.2 46 ± 3
DBA/1 H2 q m 12 50 3.2 ± 0.5 55 ± 8c
Balb/c H2 d m 5 0   
NOD H2 g7 m 10 0   
B10.P H2 p m 5 40 3.0 ± 1.0 45 ± 0
B10.RIII H2 r m 8 25 2.0 ± 0 47 ± 2
B10.V H2 v m 5 0   
B10 H2 b m 5 0   
B10.F H2 f m 5 0   
B10.U H2 u m 1 0   
  1. Only affected mice were included in the statistical analysis. aQD mice developed higher mean maximum disease scores than mice from the B10.Q, DBA/1, B10.P, and B10.RIII strains (P < 0.05). bQD mice developed disease symptoms earlier than all other strains (P < 0.05). cDBA/1 mice developed disease symptoms later than all other strains (P < 0.05). f, female; m, male; QD, (B10.Q × DBA/1)F1 mice.