Mice |
n
| Incidence (%) | Mean maximum scorea | Day of onset of symptoms |
IL-10+/- | 9 | 44 | 2.8 ± 0.8 | 68 ± 30 |
IL-10-/- | 11 | 82 | 3.5 ± 1.4* | 41 ± 6* |
- All mice were bred on a C57BL/10 background carrying the H2qhaplotype in the MHC class II region. aScore of severity of matrilin-1-induced relapsing polychondritis, from a possible maximum of 5; see Materials and methods. *P < 0.05.