| | | Total no. | Rheumatoid | | | Positive predictive |
|---|
Country | Reference | of patients | patients | Sensitivity (%) | Specificity (%) | value (%) |
Canada | [7] | 482 | 206 | 43 | 99 | 97 |
Spain | [17] | 1087 | 360 | 33 | 100 | 99 |
France | [3] | 403 | 154 | 40 | 92 | n/a |
Austria | [16] | 247 | 46 | 37 | 98 | n/a |
China | [18] | 518 | 191 | 32 | 99 | 94 |
Total | | 2737 | 957 | 37 | 98 | 97 |
- The control populations were normal individuals and patients with degenerative arthritis from the communities shown, autoimmune patients with systemic lupus erythematosus, Sjögren and other systemic connective tissue diseases, and patients with chronic arthritis of the spondylarthropathy variants. All RA patients satisfied the ACR criteria, including those with early (less than 1 year) disease. It is important to note that the data on sensitivity, specificity and positive predictive value for RA are valid only for established RA cohorts and would not necessarily apply to early synovitis cohorts, where satisfying the ACR criteria for RA at entry is not a prerequisite. n/a, not applicable.
