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Table 3 HLA-B27/Chlamydia peptide tetramer staining of CD8+ T cells from synovial fluid of six HLA-B27+ patients (nos 1–6) and three HLA-B27- patients (nos 7–9) with Chlamydia-triggered reactive arthritis

From: Use of HLA-B27 tetramers to identify low-frequency antigen-specific T cells in Chlamydia-triggered reactive arthritis

Patient no. B27 No. 68 No. 133 No. 195
1 + - - -
2 + - - +
3 + + - +
4 + - - -
5 + - + +
6 + - + -
7 - - - -
8 - - - -
9 - - - -
10 + - - -
11 + - - -
12 + - - -
13 n.d. - - -
14 n.d. - - -
15 n.d. - - -
  1. CD8+ T cells from the synovial fluid of three HLA-B27+ patients with enterobacteria-triggered reactive arthritis (patient nos 10–12), three patients with rheumatoid arthritis (patient nos 13–15) were analysed; the peripheral blood of six healthy HLA-B27+ blood donors was also analysed (not shown). Positive results are indicated with +, no staining with -. All other peptides tested negative. n.d., not done.
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