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Figure 1 | Arthritis Res Ther

Figure 1

From: The current status of targeting BAFF/BLyS for autoimmune diseases

Figure 1

Interactions of BAFF and its homologs with the three BAFF receptors. Sites of action of potential blockers are described in Table 1. APRIL, a proliferation-inducing ligand; BAFF-R, BAFF receptor; BCMA, B cell maturation antigen; ΔBAFF, alternatively spliced form of BAFF that does not bind to BAFF receptors; TACI, transmembrane activator and calcium modulator ligand interactor; TWE-PRIL, a fusion protein of TWEAK (TNFSF12) and APRIL.

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