Figure 2From: The current status of targeting BAFF/BLyS for autoimmune diseasesStages of B cell development and expression of BAFF receptors. The BAFF receptor expressed is shown in the box (1, B cell maturation antigen [BCMA]; 2, transmembrane activator and calcium modulator ligand interactor [TACI]; 3, BAFF receptor [BAFF-R]). A broken line indicates stages of differentiation that can occur independently of BAFF. The necessity of BAFF for the survival of established memory cells or of long-lived plasma cells is not yet certain.Back to article page