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Figure 2 | Arthritis Res Ther

Figure 2

From: Biology of recently discovered cytokines: Discerning the pro- and anti-inflammatory properties of interleukin-27

Figure 2

The paradoxical pro- and anti-inflammatory properties of IL-27. Through ligation of its cognate receptor, IL-27 influences a range of immune cell lineages. This figure summarizes the effects of IL-27 treatment or IL-27 receptor deficiency on mast cells, monocytes, NK cells, NK T cells, CD4+ T cells and CD8+ T cells. References are listed as bracketed citations in the far right column of the figure. IFN, interferon; IL, interleukin; NK, natural killer; TNF, tumor necrosis factor.

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Arthritis Research & Therapy

ISSN: 1478-6362

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