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Table 1 Histopathological examination of joints

From: Role of IL-12 in Staphylococcus aureus-triggered arthritis and sepsis

  Synovitis Bone/cartilage destruction
IL-12 status Frequency (%) Index Frequency (%) Index
IL-12-/- 75 3.7 ± 0.9 63 3.4 ± 1.0
IL-12+/+ 89 5.2 ± 1.2 78 6.2 ± 1.7
  1. Histopathological examination of joints from IL-12-deficient mice (n = 16) and their wild-type counterparts (n = 9) 20 days after intravenous inoculation of 1 × 107 staphylococci/mouse. All four limbs were sectioned and stained with haematoxylin and eosin. Synovial hypertrophy or bone/cartilage destruction was given a score of 1–3 for each joint location (elbow, wrist, carpal joints, fingers, knee, ankle, tarsal joints and toes). Values are expressed as percentage or mean ± standard error or the mean.