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Table 1 Histopathological examination of joints

From: Role of IL-12 in Staphylococcus aureus-triggered arthritis and sepsis

 

Synovitis

Bone/cartilage destruction

IL-12 status

Frequency (%)

Index

Frequency (%)

Index

IL-12-/-

75

3.7 ± 0.9

63

3.4 ± 1.0

IL-12+/+

89

5.2 ± 1.2

78

6.2 ± 1.7

  1. Histopathological examination of joints from IL-12-deficient mice (n = 16) and their wild-type counterparts (n = 9) 20 days after intravenous inoculation of 1 × 107 staphylococci/mouse. All four limbs were sectioned and stained with haematoxylin and eosin. Synovial hypertrophy or bone/cartilage destruction was given a score of 1–3 for each joint location (elbow, wrist, carpal joints, fingers, knee, ankle, tarsal joints and toes). Values are expressed as percentage or mean ± standard error or the mean.