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Table 3 Serum IgG isotypes in response to TSST-1 secreting Staphylococcus aureus

From: Role of IL-12 in Staphylococcus aureus-triggered arthritis and sepsis

 

IgG isotype

IL-12 status

IgG1

IgG2a

IgG3

IL-12-/-

5.9 ± 1.1

1.8 ± 0.4*

1.2 ± 0.2

IL-12+/+

4.3 ± 0.4

0.86 ± 0.0

0.97 ± 0.15

  1. Levels measured in sera 20 days after inoculation of bacteria. Values are expressed as mean ± standard error of the mean (mg/ml). IL-12-/-, n = 16; IL-12+/+, n = 8. *P = 0.03.