Figure 6

Schematic representation of the human tristetraprolin (TTP) gene (ZFP36) and its polymorphisms. The two exons of ZFP36 are shown as boxes, whereas the flanking regions and intron are indicated by a thin line. Open boxes represent untranslated regions, solid filled boxes represent protein-coding regions, and the hatched region represents the tandem zinc finger domain. The positions of the polymorphisms listed in Table 1 are indicated by arrowheads. Kb, kilobases. The data are modified from [52].