Table 1 Clinical and biological characteristics of patients with systemic sclerosis (SSc)
Characteristic | Limited SSc (n = 6) | Diffuse SSc (n = 6) |
|---|---|---|
Raynaud's phenomenon, n | 6 | 6 |
Current digital vascular ulceration, n | 0 | 0 |
Lung fibrosis (computed tomography scan), n | 2 | 4 |
Forced vital capacity <75%, n | 0 | 4 |
DLCOc/haemoglobin <80%, n | 3 | 3 |
Pulmonary hypertension (sPAP >40 mmHg), n | 0 | 0 |
Positive for anti-topoisomerase I antibodies, n | 0 | 4 |
Positive for anti-centromere antibodies, n | 3 | 0 |
Creatinine, µmol/l (range) | 73.4 ± 12.5a (56–81) | 76.4 ± 13.5a (60–90) |
ESR, mm/h | 13.6 ± 11a | 18.6 ± 15a |
C-reactive protein concentration, mg/l | 7.6 ± 6.1a | 8.8 ± 7.4a |
Low dose of prednisone (ongoing treatment), n (mean mg/day) | 2 (7) | 4 (7.5) |
Angiotensin-converting enzyme inhibitors, n | 0 | 3 |
D-Penicillamine, n | 0 | 2 |
Omeprazole, n | 6 | 6 |