Figure 2

CD123⁺ dendritic cells (DCs) and CD11c⁺ cells are enriched in rheumatoid arthritis (RA) synovial tissue (ST). CD123⁺ DCs were quantitated by counting the number of CD123⁺Ulex^- cells in sections double-stained with CD123 and Ulex. Cells were counted in each of the entire sections from three patients and three normal controls at high power, and for each biopsy this number was corrected for the area of the section to obtain the number/mm². To quantitate CD11c⁺ cellular infiltration, the number of CD11c⁺ cells was counted in three high-power fields of the synovial sublining in sections from three patients and three normal controls. Data represent means ± standard error of the mean.