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Figure 2 | Arthritis Res Ther

Figure 2

From: JNK1 is not essential for TNF-mediated joint disease

Figure 2

Histological assessment of synovial inflammation and joint destruction. No signs of arthritis are seen in the tarsal joints of wild-type (wt) and JNK1 (c-Jun N-terminal kinase 1) knockout (JNK1-/-) mice, whereas severe inflammation (I) and numerous erosions (E) are observed in human TNF transgenic (hTNFtg) and intercrossed (JNK1-/-hTNFtg) mice. H-&-E-stained sections; magnification 50×.

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