Table 1 Tapasin genotypic distributions in systemic onset juvenile rheumatoid arthritis families
Tapasin genotypes | US healthy control individuals | US healthy siblings of SoJRA | US SoJRA | UK SoJRA | UK and US SoJRA |
|---|---|---|---|---|---|
0101 | 35 (31.0%) | 26 (28.0%) | 49 (36.6%) | 23 (30.0%) | 72 (34.4%) |
0102 | 56 (49.5%) | 50 (53.7%) | 63 (47.0%) | 45 (60.0%) | 108 (51.6%) |
0202 | 22 (19.5%) | 17 (18.3%) | 22 (16.4%) | 7 (9.2%) | 29 (14.0%) |
01 allele frequency | 0.56 | 0.55 | 0.6 | 0.6 | 0.6 |
02 allele frequency | 0.44 | 0.45 | 0.4 | 0.4 | 0.4 |
Total | 113 | 93 | 134 | 76 | 209 |