Figure 3
From: Building the synovium: cadherin-11 mediates fibroblast-like synoviocyte cell-to-cell adhesion
Cadherin-11 mediates cell condensation. Cadherin-11-transfected L-cells or vector control L-cells were seeded in equal numbers. After 4 days in culture, cadherin-11-expressing L-cells formed extensive contacts along their surfaces and condensed at higher cell density to form a continuous sheet of cells. In contrast, vector control L-cells were loosely organized and did not form a tissue-like structure. (Reproduced from The Journal of Experimental Medicine 2004, 200:1677 by permission of The Rockefeller University Press [16].)