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Table 1 Description of the ligands and functions of the surface markers studied

From: Phenotypic characteristics of human monocytes undergoing transendothelial migration

Surface marker

Designation

Ligand(s)

Function

CD11a

 

CD54, CD102

Adhesion, T cell development

CD33

 

Sialylated glycoproteins?

Functions in haematopoesis

CD45RA

  

Signal transduction

CD45RB

  

Signal transduction

CD45RO

  

Signal transduction

CD49d

α4-integrin

VCAM-1, fibronectin, MAdCAM-1, invasin

Adhesion, embryonic development

CD54

ICAM-1

LFA-1 (CD11a/CD18), Mac-1 (CD11b/CD18), CD43

Adhesion, leucocyte transendothelial migration, signal transduction

CD62L

L-selectin

DNAd (CD34, GlyCAM-1, MAdCAM-1)

Adhesion; leucocyte homing, rolling and extravasation

CD86

B 7-2

CD28, CD152

T cell interaction with dendritic cells and B cells, B cell co-stimulation