Feature | Scoring system |
---|---|
Assessed by histology | Â |
   Lining-layer hyperplasia | Semiquantitative |
   Degree of vascularity | Semiquantitative |
   Inflammatory infiltration | Semiquantitative |
   Lymphoid aggregates | Present or absent |
   Plasma cells | Semiquantitative |
   Polymorphonuclear leukocytes | Semiquantitative |
Assessed by immunohistochemistry | Â |
   CD1a | Present or absent |
   CD3 | Semiquantitative |
   CD20 | Semiquantitative |
   CD68 lining layer | Semiquantitative |
   CD68 sublining layer | Semiquantitative |
   CD163 lining layer | Semiquantitative |
   CD163 sublining layer | Semiquantitative |
   Intracellular citrullinated peptides | Present or absent |
   MHC class II–HC gp39 peptide complex, recognized by mAb 12A | Present or absent |