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Table 3 Factor analysis on cytokines and neuropeptides in synovial fluid

From: Levels of gastrin-releasing peptide and substance P in synovial fluid and serum correlate with levels of cytokines in rheumatoid arthritis

Variable

Factor

 

1

2

3

4

TNF-α

 

0.751

  

IL-6

  

0.913

 

MCP-1

 

0.912

  

BN/GRP

-0.436

 

0.623

0.327

SP

0.409

0.33

0.361

0.671

VIP

0.784

   

CGRP

0.715

  

-0.472

NPY

0.893

   

ESR

   

0.71

  1. Principal-component analysis for cytokines and neuropeptides in synovial fluid from 23 patients with long-standing RA, and for the ESR. BN/GRP, bombesin/gastrin-releasing peptide; CGRP, calcitonin-gene-related peptide; ESR, erythrocyte sedimentation rate; MCP, monocyte chemoattractant protein-1; NPY, neuropeptide Y; RA, rheumatoid arthritis; SP, substance P; TNF, tumour necrosis factor; VIP, vasoactive intestinal peptide.