Expression of cytokine mRNA and protein in joints and lymphoid organs during the course of rat antigen-induced arthritis

Table 2 Correlation between mRNA expression and severity of knee joint swelling in rats with AIA

Cytokine	Day(s)	Correlation^a	P ^a	ρ^a	n
Synovial membrane
IL-1β	0–6	+	0.05	0.527	25
IL-6	0–6	+	0.03	0.405	28
Inguinal lymph node
IL-6	3	+	0.02	0.886	6
Spleen
IL-6	0–6	+	0.01	0.511	25
IL-5	6	-	<0.001	1.000	4
IL-10	6	-	0.04	0.829	6

^aSpearman rank correlation. +, positive; -, negative; AIA, antigen-induced arthritis.

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