Table 1 Summary of the conflicting data on QTc interval in adults and in infants
Group | Reference | Characteristic | Anti-SSA/Ro-positive group | Control group | P |
|---|---|---|---|---|---|
Infants | [2] | No. of patients | 21 | 7 | |
Age (days) | 90 | 7 | NA | ||
QTc (ms) | 442 ± 35 | 403 ± 16 | 0.001 | ||
[3] | No. of patients | 38 | 7 | ||
Age (months) | 65.4 | 1.8 | NA | ||
QTc (ms) | 379 ± 26 | 332 ± 20 | <0.0001 | ||
[8] | No. of patients | 58 | 85 | ||
Age (days) | 13 ± 14 | 15 ± 16 | 0.31 | ||
QTc (ms) | 397 ± 27 | 395 ± 25 | 0.57 | ||
Adults | [9] | No. of patients | 31 | 26 | |
Age (years) | 41 ± 15 | 49 ± 13 | NA | ||
QTc (ms) | 445 ± 21 | 419 ± 17 | 0.000005 | ||
[20] | No. of patients | 49 | 62 | ||
Age (years) | 46 | 44 | NS | ||
QTc (ms) | 411 ± 19 | 403 ± 24 | 0.06 | ||
[21] | No. of patients | 32 | 57 | ||
Age (years) | 37 ± 11 | 38 ± 12 | 0.58 | ||
QTc (ms) | 409 ± 30 | 409 ± 28 | 0.78 |