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Table 1 Summary of the conflicting data on QTc interval in adults and in infants

From: Anti-SSA/Ro antibodies and the heart: more than complete congenital heart block? A review of electrocardiographic and myocardial abnormalities and of treatment options

Group Reference Characteristic Anti-SSA/Ro-positive group Control group P
Infants [2] No. of patients 21 7  
   Age (days) 90 7 NA
   QTc (ms) 442 ± 35 403 ± 16 0.001
  [3] No. of patients 38 7  
   Age (months) 65.4 1.8 NA
   QTc (ms) 379 ± 26 332 ± 20 <0.0001
  [8] No. of patients 58 85  
   Age (days) 13 ± 14 15 ± 16 0.31
   QTc (ms) 397 ± 27 395 ± 25 0.57
Adults [9] No. of patients 31 26  
   Age (years) 41 ± 15 49 ± 13 NA
   QTc (ms) 445 ± 21 419 ± 17 0.000005
  [20] No. of patients 49 62  
   Age (years) 46 44 NS
   QTc (ms) 411 ± 19 403 ± 24 0.06
  [21] No. of patients 32 57  
   Age (years) 37 ± 11 38 ± 12 0.58
   QTc (ms) 409 ± 30 409 ± 28 0.78
  1. NA, not available; NS, not significant. Data are presented as means ± SD when available.