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Table 2 Characteristics of human herpesviruses, Chlamydiae and parvovirus

From: Amplification of autoimmune disease by infection

Organism Receptors Main cellular tropism Proposed latency cell Other tropism References
EBV CD21, MHC-II, α5β1 integrin B B EPC, EC [8]
CMV EGFR M/M M/M; EC N, EPC, EC [174]
HHV6 CD46+ M/M, T, B M/M N, EPC [175]
HHV7 CD4+ heparan sulfate receptor T M/M N, EPC, EC [176,177]
HHV8 Heparan sulfate receptor, EGFR EC, M/M, B, T B N, EPC [174,178]
Chlamydia pneumoniae Heparan sulfate receptor M/M   EC, EPC [179]
Chlamydia trachomatis   M/M   EC, EPC  
Parvovirus B19 Erythrocyte P antigen Erythroid precursors   EC [66,67]
  1. B, B cells; CMV, cytomegalovirus; EBV, Epstein–Barr virus; EC, endothelial cells; EGFR, epidermal growth factor receptor; EPC, epithelial cells; HHV, human herpesvirus; MHC, major histocompatibility complex; M/M, myelomonocytic cells; N, neural cells; T, T cells.